产品详情 |
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Antigenic Specificity | CAND1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:1,000-1:5,000, Immunoprecipitation: 2-5 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CAND1 Polyclonal Antibody. CAND1 enhances transcription from various types of promoters. It is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site. CAND1 disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins. |
Immunogen | n/a |
Other Names | Cullin-associated and neddylation-dissociated 1, DKFZp434M1414, FLJ10114, FLJ10929, FLJ38691, FLJ90441, KIAA0829, TIP120, TIP120A |
Gene, Accession # | Entrez: 55832, 71902; Uniprot: Q6ZQ38, Q86VP6 |
Catalog # | A302-901A |
Price | |
Order / More Info | CAND1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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