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| Product Name | QuickDetect™ 24(S)-Hydroxycholesterol (Human) ELISA Kit |
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| Description | An important cholesterol metabolite (cholesterol 24-hydroxylase) found in the brain. It is an endogenous agonist of the nuclear receptor LXR. It has been shown to induce cell death in neuroblastoma cells, possibly via a necroptosis pathway. 24(S)-Hydroxycholesterol has also been found to be a high affinity ligand for RORα and RORγ (Ki = 25 nM). 24(S)-Hydroxycholesterol levels are elevated in the cerebral spinal fluids of patients with neurogenerative diseases suggesting possible clinical applications. It was also able to reduce Aβ production and increase ER-resident immature amyloid precursor protein (APP) levels in human neuroblastoma SH-Sy5Y cells and CHO cells via inhibition of intracellular amyloid precursor protein tra |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | This ELISA kit is used for quantitative measurement of 24-OHC in human serum, plasma, cell culture supernatant and other biological fluids. |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K4434-100 |
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| Order / More Info | QuickDetect™ 24(S)-Hydroxycholesterol (Human) ELISA Kit from BIOVISION, INC. |
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| Product Specific References | n/a |
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