| 产品详情 |
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| Product Name | Linsitinib, Free base |
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| Description | A potent, small-molecule dual insulin-like growth factor-1 receptor (IGF-1R)/insulin receptor (IR) kinase inhibitor. Inhibits IGF-1R and IR kinases with IC50 values of 35 nM and 75 nM, respectively. Linsitinib selectively blocks the autophosphorylation of both human IGF-1R and IR, inhibits the proliferation of a variety of tumor cell lines in vitro, and displays robust in vivo anti-tumor efficacy in an IGF-1R-driven xenograft model when administered orally. MW: 421.49. Purity ≥99% by HPLC |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (1S,3S)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutanol; OSI-906; OSI 906AA |
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| Gene, Accession, CAS # | CAS: 867160-71-2 |
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| Catalog # | 2294-5 |
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| Order / More Info | Linsitinib, Free base from BIOVISION, INC. |
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| Product Specific References | n/a |
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