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Product Name | Jumonji HDM Inhibitor, PBIT |
Description | PBIT is a potent, cell-permeable inhibitor of Jumonji histone demethylase (JHDM). Innhibits JARID1B (also known as KDM5B or PLU1) with an IC50 of about 3 µm in vitro. PBIT treatment inhibits removal of H3K4me3 by JARID1B in cells and inhibits proliferation of cells expressing higher levels of JARID1B. MW: 241.31. Purity ≥98% by HPLC |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-4(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one |
Gene, Accession, CAS # | CAS: 2514-30-9 |
Catalog # | 2475-5 |
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Order / More Info | Jumonji HDM Inhibitor, PBIT from BIOVISION, INC. |
Product Specific References | n/a |
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