| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD172a (SIRP alpha) |
|---|
| Clone | P84 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG1, kappa |
|---|
| Format | unconjugated, functional grade |
|---|
| Size | 50 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 0.25 µg/test, Functional Assay: Assay-Dependent |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD172a (SIRP alpha) Monoclonal Antibody (P84), Functional Grade, eBioscience™. CD172a, also known as signal-regulatory protein alpha, is a receptor-type transmembrane glycoprotein expressed on cells of myeloid origin, including granulocytes, dendritic cells (DCs), macrophages, mast cells and haematopoietic stem cells. CD172a acts as a substrate for several activated tyrosine kinases, including EGFR, PDGFR, src and insulin receptor and is involved in the negative regulation of receptor tyrosine kinase-coupled signaling pathways. Ligand binding of CD172a to integrin-associated protein CD47, results in tyrosine kinase phosphorylation of immunoreceptor tyrosine-based inhibitory motifs (ITIMs) within the cytoplasmic region of CD172a, media |
|---|
| Immunogen | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession # | Entrez: 19261; Uniprot: P97797 |
|---|
| Catalog # | 16-1721-81 |
|---|
| Price | |
|---|
| Order / More Info | CD172a (SIRP alpha) Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 22457345, 22547652 |
|---|
| 产品资料 |
|
|