(Click to see larger image) Narishige's NMN-21 is a manually operated micromanipulator which minimizes jitter for simplicity and high performance.

Drift and electromagnetic disturbance are critical problems in patch clamping work.  This mechanical micromanipulator was developed specifically for patch clamping:  it does not employ a liquid hydraulic system (which is prone to drift due to temperature changes), has no springs (a common cause of mechanical drift), nor a motor (which can be a source of electrical noise).  Its body is designed to absorb vibrations, so that even at high magnifications, problems of jittering are virtually non-existant.  The NMN-21 is based on a drum type design and utilizes a pair of independent sliders that serve to isolate vibrations. In addition, vibrations are often caused by the operator handling the control knob, which is usually connected to a slider. To overcome this problem, the control knob of the NMN-21 is fixed independently and separate from the slider.  High mass and a low center of gravity provide exceptionally steady and stable performance.  The overall design is compact, so installation requires a minimum of space.  With coarse and fine manipulators integrated into the compact body, this model handles a full range of required motions, from moving a microelectrode into the microscope field of view to making delicate contact with cells.

* Can be mounted directly on an optical bench-type isolation table
* Can be firmly fixed to any part of a steel isolation table with the NMN-C magnetic stand (sold separately)
* Can be mounted directly to microscopes via suitable adapters (sold separately)
* AP-14/AP-13-3 patch clamp headstage holders can be attached via the integrated UST-2 solid universal joint

Setting Example
The first photo shows a mounting adapter setting example. The second photo shows the setting example with the ITS2-N/ ITS2-O/ ITS2-Z/ ITS2-L (Microscope Isolation Systems) plus NR-12 (Rotating Micromanipulator Clamp) plus NMN-21.


Specification