产品名称 SC 79
产品货号 Axon 2507 CAS [305834-79-1] MF C17H17ClN2O5MW 364.78 Purity: 98% Soluble in DMSO Description Unique specific activator of cytosolic Akt (PKB) with the potential to recapitulate the primary cellular function of Akt signaling in a hippocampal neuronal culture system and a mouse model for ischemic stroke, resulting in augmented neuronal survival. Paradoxically, SC 79 suppressed PH-Akt-GFP plasma membrane translocation. Close analogue of HA 14-1 (Axon 2007), a Bcl-2 antagonist (IC50 value 9 µM). KEYWORDS: SC 79 | supplier | Akt activator | SC79 |CAS [305834-79-1] | Phosphatidylinositol | Akt | Activator | PKB | cytosolic | phosphorylation | ischemia | neuronal death | stroke | Bcl-2 | HA14-1 | plecstrin homolog | translocation
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SC 79

Based on 26 publications in PubMed 10 10 26

Axon 2507

CAS [305834-79-1]

MF C17H17ClN2O5
MW 364.78

  • Purity: 98%
  • Soluble in DMSO

SC 79

Description

Unique specific activator of cytosolic Akt (PKB) with the potential to recapitulate the primary cellular function of Akt signaling in a hippocampal neuronal culture system and a mouse model for ischemic stroke, resulting in augmented neuronal survival. Paradoxically, SC 79 suppressed PH-Akt-GFP plasma membrane translocation.

Close analogue of HA 14-1 (Axon 2007), a Bcl-2 antagonist (IC50 value 9 µM).

KEYWORDS: SC 79 | supplier | Akt activator | SC79 |CAS [305834-79-1] | Phosphatidylinositol | Akt | Activator | PKB | cytosolic | phosphorylation | ischemia | neuronal death | stroke | Bcl-2 | HA14-1 | plecstrin homolog | translocation

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