| 产品名称 | L 002 - NSC 764414 |
| 产品货号 | Axon 2319 CAS [321695-57-2] MF C15H15NO5SMW 321.35 Purity: 99% Soluble in DMSO Description Inhibitor of p300 histone acyltransferase (a.k.a KAT3B; IC50 value 1.98 μM in vitro) that also inhibited acetylation of histones and p53, and suppresses STAT3 activation in cell-based assays. In vivo, L 002 potently suppressed tumor growth of TNBC cell line MDA-MB-468 xenografts. References Certificates Categories Extra info H. Yang et al. Small-molecule inhibitors of acetyltransferase p300 identified by high-throughput screening are potent anticancer agents. Mol. Cancer Ther. 2013, 12, 610-620. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Epigenetics HAT p53 Transcription Factors p53-Tumor Suppression NF-κB JAK-STAT EC 2.3.1.48 Inhibitor of p300 HAT (KAT3B) and p53 acetylation Chemical name 4-(4-methoxyphenylsulfonyloxyimino)-2,6-dimethylcyclohexa-2,5-dienone Parent CAS No. [321695-57-2] Order Size Unit Price Stock 10 mg €80.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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L 002 - NSC 764414Axon 2319 CAS [321695-57-2] MF C15H15NO5S
Description
Inhibitor of p300 histone acyltransferase (a.k.a KAT3B; IC50 value 1.98 μM in vitro) that also inhibited acetylation of histones and p53, and suppresses STAT3 activation in cell-based assays. In vivo, L 002 potently suppressed tumor growth of TNBC cell line MDA-MB-468 xenografts.
Inhibitor of p300 HAT (KAT3B) and p53 acetylation
Chemical name4-(4-methoxyphenylsulfonyloxyimino)-2,6-dimethylcyclohexa-2,5-dienone Parent CAS No.[321695-57-2] |
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