| 产品名称 | BAY 11-7082 - BAY 11-7821 |
| 产品货号 | Axon 2132 CAS [19542-67-7] MF C10H9NO2SMW 207.25 Purity: 99% Soluble in DMSO Description IKK inhibitor and broad-spectrum inhibitor with anti-inflammatory activity against multiple targets. BAY strongly suppressed the production of nitric oxide, prostaglandin E2, and TNF-α and reduced the translocation of p65, major subunit of nuclear factor-κB, and its upstream signaling events such as phosphorylation of IκBα, IKK, and Akt. In addition, BAY also inhibits the phosphorylation or activation of extracellular signal-related kinase, p38, TANK-binding protein, and JAK-2. References Certificates Categories Extra info J Lee et al. BAY 11-7082 Is a Broad-Spectrum Inhibitor with Anti-Inflammatory Activity against Multiple Targets. Med. Inflammation, 2012, Article ID 416036. M Ghashghaeinia et al. The NFĸB pathway inhibitors Bay 11-7082 and parthenolide induce programmed cell death in anucleated Erythrocytes. Cell Physiol. Biochem. 2011, 27, 45-54. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Immunology Pain & Inflammation Transcription Factors NF-κB EC 2.7.11.10 IKK IKK inhibitor and anti-inflammatory Chemical name (E)-3-(p-tolylsulfonyl)acrylonitrile Parent CAS No. [19542-67-7] Order Size Unit Price Stock 10 mg €85.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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BAY 11-7082 - BAY 11-7821Axon 2132 CAS [19542-67-7] MF C10H9NO2S
Description
IKK inhibitor and broad-spectrum inhibitor with anti-inflammatory activity against multiple targets. BAY strongly suppressed the production of nitric oxide, prostaglandin E2, and TNF-α and reduced the translocation of p65, major subunit of nuclear factor-κB, and its upstream signaling events such as phosphorylation of IκBα, IKK, and Akt. In addition, BAY also inhibits the phosphorylation or activation of extracellular signal-related kinase, p38, TANK-binding protein, and JAK-2.
IKK inhibitor and anti-inflammatory
Chemical name(E)-3-(p-tolylsulfonyl)acrylonitrile Parent CAS No.[19542-67-7] |
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