产品名称 Purmorphamine
产品货号 Axon 1690 CAS [483367-10-8] MF C31H32N6O2MW 520.62 Purity: 99% Soluble in DMSO Description Hedgehog (Hh) agonist that directly targets Smoothened (SMO) transmembrane protein. Purmorphamine up-regulates gene expression of mediators of Hh pathway, SMO, PTCH1, GLI1, and GLI2, and induces osteoblast differentiation of multipotent mesenchymal progenitor cells and lineage-committed preosteoblasts. References Certificates Categories Extra info S. Sinha et al. Purmorphamine activates the Hedgehog pathway by targeting Smoothened. Nat. Chem. Biol. 2006, 2, 29-30.   F.S. Oliveira et al. Hedgehog signaling and osteoblast gene expression are regulated by purmorphamine in human mesenchymal stem cells. J. Cell. Biochem. 2012, 113, 204–208. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Stem Cell Smoothened (SMO) Hedgehog F Stem Cell Differentiator Hedgehog signaling pathway activator Chemical name 9-cyclohexyl-N-(4-morpholinophenyl)-2-(naphthalen-1-yloxy)-9H-purin-6-amine Parent CAS No. [483367-10-8] Order Size Unit Price Stock 5 mg €105.00 In Stock
产品价格 现货询价,电话:010-67529703
产品规格
产品品牌 axonmedchem
产品概述
产品详情

Purmorphamine

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1690

CAS [483367-10-8]

MF C31H32N6O2
MW 520.62

  • Purity: 99%
  • Soluble in DMSO

Purmorphamine

Description

Hedgehog (Hh) agonist that directly targets Smoothened (SMO) transmembrane protein. Purmorphamine up-regulates gene expression of mediators of Hh pathway, SMO, PTCH1, GLI1, and GLI2, and induces osteoblast differentiation of multipotent mesenchymal progenitor cells and lineage-committed preosteoblasts.
产品资料