| 产品名称 | GDC 0449 - Vismodegib | HhAntag 691 |
| 产品货号 | Axon 1500 CAS [879085-55-9] MF C19H14Cl2N2O3SMW 421.30 Purity: 99% Soluble in DMSO Description The first-in-class inhibitor of Hedgehog (Hh) signaling pathway; more specifically, an orally bioavailable and potent inhibitor of smoothened homologue (SMO); an investigational anti-cancer drug for Medulloblastoma, advanced basal cell skin cancer etc References Certificates Categories Extra info CM Rudin et al. Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449. N. Engl. J. Med. 2009, 361, 1173-8. SJ Scales and FJ de Sauvage. Mechanisms of Hedgehog pathway activation in cancer and implications for therapy. Trends Pharmacol. Sci. 2009, 30(6), 303-312. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology CNS Stem Cell Smoothened (SMO) Hedgehog F Hedgehog (Hh) pathway inhibitor Chemical name 2-Chloro-N-(4-chloro-3-pyridin-2-yl-phenyl)-4-methanesulfonyl-benzamide Parent CAS No. [879085-55-9] Order Size Unit Price Stock 5 mg €80.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
| 产品概述 | |
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GDC 0449 - Vismodegib | HhAntag 691Axon 1500 CAS [879085-55-9] MF C19H14Cl2N2O3S
Description
The first-in-class inhibitor of Hedgehog (Hh) signaling pathway; more specifically, an orally bioavailable and potent inhibitor of smoothened homologue (SMO); an investigational anti-cancer drug for Medulloblastoma, advanced basal cell skin cancer etc
Hedgehog (Hh) pathway inhibitor
Chemical name2-Chloro-N-(4-chloro-3-pyridin-2-yl-phenyl)-4-methanesulfonyl-benzamide Parent CAS No.[879085-55-9] |
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