产品名称

ML348

产品货号

Axon 2646 CAS [899713-86-1] MF C18H17ClF3N3O3MW 415.79 Purity: 99% Soluble in DMSO Description Selective and in vivo active inhibitor for acyl-protein thioesterase APT1 (IC50 values 0.84 µM and >10 µM for APT1 and APT2, respectively; Ki values 280 nM and >10000 nM for WT APT1 and APT2, respectively). A useful tool to study LYPLA/APT mediated protein S-palmitoylation and related pharmacology. In some of the literature, APT1 and APT2 are also identified as lysophospholipases LYPLA1 and LYPLA2 as they were first discovered due to their ability to hydrolyze various lysophospholipids. KEYWORDS: ML348 | supplier | APT1 inhibitor | ML-348 | CAS [899713-86-1] | S-palmitoylated proteins | APT | acyl-protein thioesterase | LYPLA | APT2 | LYPLA1 | LYPLA2 | lysophospholipids

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

ML348

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2646

CAS [899713-86-1]

MF C18H17ClF3N3O3
MW 415.79

Purity: 99%
Soluble in DMSO

ML348

Description

Selective and in vivo active inhibitor for acyl-protein thioesterase APT1 (IC50 values 0.84 µM and >10 µM for APT1 and APT2, respectively; Ki values 280 nM and >10000 nM for WT APT1 and APT2, respectively). A useful tool to study LYPLA/APT mediated protein S-palmitoylation and related pharmacology. In some of the literature, APT1 and APT2 are also identified as lysophospholipases LYPLA1 and LYPLA2 as they were first discovered due to their ability to hydrolyze various lysophospholipids.