产品名称 DDR1-IN-1
产品货号 Axon 2265 CAS [1449685-96-4] MF C30H31F3N4O3MW 552.59 Purity: 98% Soluble in DMSO Description Potent and selective DDR1 receptor tyrosine kinase (RTK) inhibitor (IC50 values 105 and 413 nM for DDR1 and DDR2 respectively); a useful pharmacological probe for DDR1-dependent signal transduction. References Certificates Categories Extra info H.G. Kim et al. Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor. A.C.S. Chem. Biol. 2014, 9, 840.   P. Canning et al. Structural mechanisms determining inhibition of the collagen receptor DDR1 by selective and multi-targeted type II kinase inhibitors. J. Mol. Biol. 2014, 426, 2457-2470. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology DDR1 RTK class XVI; EC 2.7.10.1 Selective DDR1 receptor tyrosine kinase (RTK) inhibitor Chemical name 4-((4-Ethylpiperazin-1-yl)methyl)-N-(4-methyl-3-(2-oxoindolin-5-yloxy)phenyl)-3-(trifluoromethyl)benzamide Parent CAS No. [1449685-96-4] Order Size Unit Price Stock 5 mg €95.00 In Stock
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DDR1-IN-1

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2265

CAS [1449685-96-4]

MF C30H31F3N4O3
MW 552.59

  • Purity: 98%
  • Soluble in DMSO

DDR1-IN-1

Description

Potent and selective DDR1 receptor tyrosine kinase (RTK) inhibitor (IC50 values 105 and 413 nM for DDR1 and DDR2 respectively); a useful pharmacological probe for DDR1-dependent signal transduction.
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