产品名称 | NSC 405020 |
产品货号 | Axon 2162 CAS [7497-07-6] MF C12H15Cl2NOMW 260.16 Purity: 99% Soluble in DMSO Description MT1-MMP inhibitor (IC50>100 μM that specifically targets the hemopexin (PEX) domain. NSC 405020 shows significant antitumor efficacy in in vivo tests after intratumoral injections (0.5 mg/kg), and causes a fibrotic tumor phenotype and increases the level of COL-I. References Certificates Categories Extra info A.G. Remacle et al. Novel MT1-MMP small-molecule inhibitors based on insights into hemopexin domain function in tumor growth. Cancer Res. 2012, 72, 2339-2349. Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology Miscellaneous Pain & Inflammation EC 3.4.24.80 MMP MT1-MMP inhibitor specifically targeting PEX-domain. Chemical name 3,4-dichloro-N-(pentan-2-yl)benzamide Parent CAS No. [7497-07-6] Order Size Unit Price Stock 10 mg €85.00 In Stock |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
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NSC 405020Axon 2162 CAS [7497-07-6] MF C12H15Cl2NO
Description
MT1-MMP inhibitor (IC50>100 μM that specifically targets the hemopexin (PEX) domain. NSC 405020 shows significant antitumor efficacy in in vivo tests after intratumoral injections (0.5 mg/kg), and causes a fibrotic tumor phenotype and increases the level of COL-I.
MT1-MMP inhibitor specifically targeting PEX-domain.
Chemical name3,4-dichloro-N-(pentan-2-yl)benzamide Parent CAS No.[7497-07-6] |
产品资料 |