产品名称 NSC 405020
产品货号 Axon 2162 CAS [7497-07-6] MF C12H15Cl2NOMW 260.16 Purity: 99% Soluble in DMSO Description MT1-MMP inhibitor (IC50>100 μM that specifically targets the hemopexin (PEX) domain. NSC 405020 shows significant antitumor efficacy in in vivo tests after intratumoral injections (0.5 mg/kg), and causes a fibrotic tumor phenotype and increases the level of COL-I. References Certificates Categories Extra info A.G. Remacle et al. Novel MT1-MMP small-molecule inhibitors based on insights into hemopexin domain function in tumor growth. Cancer Res. 2012, 72, 2339-2349.  Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology Miscellaneous Pain & Inflammation EC 3.4.24.80 MMP MT1-MMP inhibitor specifically targeting PEX-domain. Chemical name 3,4-dichloro-N-(pentan-2-yl)benzamide Parent CAS No. [7497-07-6] Order Size Unit Price Stock 10 mg €85.00 In Stock
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NSC 405020

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2162

CAS [7497-07-6]

MF C12H15Cl2NO
MW 260.16

  • Purity: 99%
  • Soluble in DMSO

NSC 405020

Description

MT1-MMP inhibitor (IC50>100 μM that specifically targets the hemopexin (PEX) domain. NSC 405020 shows significant antitumor efficacy in in vivo tests after intratumoral injections (0.5 mg/kg), and causes a fibrotic tumor phenotype and increases the level of COL-I.
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