产品名称 | Apilimod dimesylate - STA 5326 dimesylate |
产品货号 | Axon 2500 CAS [870087-36-8] MF C23H26N6O2.2CH4O3SMW 610.70 Purity: 98% Soluble in water and DMSO Description Potent and orally active inhibitor of the cytokines interleukin-12 (IL-12), and interleukin-23 (IL-23) production; potential regulators of certain autoimmune and inflammatory diseases. Blocks the translocation of c-Rel, a member of the Rel/NF-κB family of transcription factors, to the nucleus without affecting the translocation of the other NF-κB family members. Water soluble dimesylate salt of Axon 1369. Note |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
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Apilimod dimesylate - STA 5326 dimesylateAxon 2500 CAS [870087-36-8] MF C23H26N6O2.2CH4O3S
DescriptionPotent and orally active inhibitor of the cytokines interleukin-12 (IL-12), and interleukin-23 (IL-23) production; potential regulators of certain autoimmune and inflammatory diseases. Blocks the translocation of c-Rel, a member of the Rel/NF-κB family of transcription factors, to the nucleus without affecting the translocation of the other NF-κB family members. Note: This item is currently suspended due to the request of the developer. You might request a quotation for contract research synthesis. Please contact us for conditions and more detailed information. KEYWORDS: Apilimod mesylate | supplier | IL-12/23 inhibitor | STA 5326 mesylate | STA5326 | CAS [870087-36-8] | [541550-19-0] | Interleukin | IL-12 | IL-23 | autoimmune | inflammation | translocation | c-Rel | NF-κB | transcription factor
Cytokine inhibitor; IL-12 and IL-23 inhibitor
Chemical name4-(6-(2-(3-methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine dimethanesulfonate Parent CAS No.[541550-19-0] |
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