产品名称

Apilimod - STA 5326

产品货号

Axon 1369 CAS [541550-19-0] MF C23H26N6O2MW 418.49 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Potent and orally active inhibitor of the cytokines interleukin-12 (IL-12), and interleukin-23 (IL-23) production; potential regulators of certain autoimmune and inflammatory diseases.The water-soluble dimesylate salt is available as well (Axon 2500). Note:

产品价格

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产品规格

产品品牌

axonmedchem

产品概述

产品详情

Apilimod - STA 5326

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1369

CAS [541550-19-0]

MF C23H26N6O2
MW 418.49

Purity: 99%
Soluble in 0.1N HCl(aq) and DMSO

Apilimod

Description

Potent and orally active inhibitor of the cytokines interleukin-12 (IL-12), and interleukin-23 (IL-23) production; potential regulators of certain autoimmune and inflammatory diseases.
The water-soluble dimesylate salt is available as well (Axon 2500).

Note: This item is currently suspended due to the request of the developer. You might request a quotation for contract research synthesis. Please contact us for conditions and more detailed information.

Wada et al: Selective abrogation of Th1 response by STA-5326, a potent IL-12/IL-23 inhibitor. Blood, 2007, 109(3), 1156-1164.

Wada et al: IL-12/IL-23 inhibitors: a promising approach to the treatment of inflammatory disorders. Drugs Fut. 2008, 33(1), 49-63.

Cytokine inhibitor; IL-12 and IL-23 inhibitor

Chemical name

N-[6-Morpholin-4-yl-2-(2-pyridin-2-yl-ethoxy)-pyrimidin-4-yl]-N'-[1-m-tolyl-meth-(E)-ylidene]-hydrazine

Parent CAS No.

[541550-19-0]

产品资料