产品名称 | Necrostatin-1 |
产品货号 | Axon 1258 CAS [4311-88-0] MF C13H13N3OSMW 259.33 Purity: 99% Soluble in DMSO Description A cell-permeable, potent, and selective inhibitor of necroptosis; Acts as a selective and ATP-competitive inhibitor of RIP1 kinase with negligible effect of RIP2 kinase activity References Certificates Categories Extra info A. Degterev et al. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nature Chem. Biol. 2008, 4, 313-321. A. Degterev et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nature Chem. Biol. 2005, 1, 112. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology Immunology Pain & Inflammation NF-κB MAPK DNA-damage Response EC 2.7.11.1 RIP RIP1 inhibitor Chemical name 5-((1H-indol-3-yl)methyl)-3-methyl-2-thioxoimidazolidin-4-one Parent CAS No. [4311-88-0] Order Size Unit Price Stock 25 mg €95.00 In Stock |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | |
产品品牌 | axonmedchem |
产品概述 | |
产品详情 |
Necrostatin-1Axon 1258 CAS [4311-88-0] MF C13H13N3OS
Description
A cell-permeable, potent, and selective inhibitor of necroptosis; Acts as a selective and ATP-competitive inhibitor of RIP1 kinase with negligible effect of RIP2 kinase activity
RIP1 inhibitor
Chemical name5-((1H-indol-3-yl)methyl)-3-methyl-2-thioxoimidazolidin-4-one Parent CAS No.[4311-88-0] |
产品资料 |