产品名称 Necrostatin-1
产品货号 Axon 1258 CAS [4311-88-0] MF C13H13N3OSMW 259.33 Purity: 99% Soluble in DMSO Description A cell-permeable, potent, and selective inhibitor of necroptosis; Acts as a selective and ATP-competitive inhibitor of RIP1 kinase with negligible effect of RIP2 kinase activity References Certificates Categories Extra info A. Degterev et al. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nature Chem. Biol. 2008, 4, 313-321.    A. Degterev et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nature Chem. Biol. 2005, 1, 112.  Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology Immunology Pain & Inflammation NF-κB MAPK DNA-damage Response EC 2.7.11.1 RIP RIP1 inhibitor Chemical name 5-((1H-indol-3-yl)methyl)-3-methyl-2-thioxoimidazolidin-4-one Parent CAS No. [4311-88-0] Order Size Unit Price Stock 25 mg €95.00 In Stock
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Necrostatin-1

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1258

CAS [4311-88-0]

MF C13H13N3OS
MW 259.33

  • Purity: 99%
  • Soluble in DMSO

Necrostatin-1

Description

A cell-permeable, potent, and selective inhibitor of necroptosis; Acts as a selective and ATP-competitive inhibitor of RIP1 kinase with negligible effect of RIP2 kinase activity
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