产品名称 | Rosiglitazone - BRL 49653 | Rezult | Rosiglizole | TDZ 01 |
产品货号 | Axon 2443 CAS [122320-73-4] MF C18H19N3O3SMW 357.43 Purity: 98% Soluble in DMSO Description High affinity PPARγ agonist (Kd value 7 nM). BRL 49653 is an antidiabetic drug and insulin sensitizer that also promotes differentiation of C3H10T1/2 stem cells to adipocytes. References Certificates Categories Extra info Y.F. Zhang et al. Rosiglitazone, a Peroxisome Proliferator-Activated Receptor (PPAR)-γ Agonist, Attenuates Inflammation Via NF-κB Inhibition in Lipopolysaccharide-Induced Peritonitis. Inflammation. 2015 Jun 6. J.M. Lehmann et al. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem. 1995 Jun 2;270(22):12953-6. R.T. Nolte et al. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma. Nature. 1998 Sep 10;395(6698):137-43. J.C. de Groot et al. Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ. J Med Chem. 2013 Feb 28;56(4):1535-43. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Diabetes & Metabolism Pain & Inflammation NF-κB PPAR NR1C PPARγ agonist; antidiabetic drug and stem cell differentiator Chemical name 5-(4-(2-(methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione Parent CAS No. [122320-73-4] Order Size Unit Price Stock 10 mg €95.00 In Stock |
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产品品牌 | axonmedchem |
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Rosiglitazone - BRL 49653 | Rezult | Rosiglizole | TDZ 01Axon 2443 CAS [122320-73-4] MF C18H19N3O3S
Description
High affinity PPARγ agonist (Kd value 7 nM). BRL 49653 is an antidiabetic drug and insulin sensitizer that also promotes differentiation of C3H10T1/2 stem cells to adipocytes.
PPARγ agonist; antidiabetic drug and stem cell differentiator
Chemical name5-(4-(2-(methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione Parent CAS No.[122320-73-4] |
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