产品名称

ZD 9379

产品货号

Axon 2261 CAS [170142-20-8] MF C19H14ClN3O4MW 383.79 Purity: 100% Soluble in 0.1N NaOH(aq) and DMSO Description Selective antagonist of the glycine site on the NMDA receptor complex. ZD9379 crosses the blood-brain barrier and is neuroprotective. In vivo studies demonstrated reduced infarct size and less spreading depressions after treatment with ZD 9379. References Certificates Categories Extra info T.M. Bare et al. Pyridazino[4,5-b]quinolinediones: novel glycine/N-methyl-D-aspartate antagonists for the treatment of stroke. J. Heterocyclic Chem. 1998, 35, 1171-1186. T. Tatlisumak et al. A glycine site antagonist ZD9379 reduces number of spreading depressions and infarct size in rats with permanent middle cerebral artery occlusion. Acta Neurochir. Suppl. 2000, 76, 331-333. K. Takano et al. Glycine site antagonist attenuates infarct size in experimental focal ischemia. Postmortem and diffusion mapping studies. Stroke. 1997, 28, 1255-1262. Certificate of Analysis Material Safety Data Sheet Cardiovascular CNS Pain & Inflammation NMDA Unclassified Antagonist of the glycine site on the NMDA receptor complex Chemical name 7-chloro-2-(4-methoxy-2-methylphenyl)-2,3-dihydropyridazino[4,5-b]quinoline-1,4,10(5H)-trione Parent CAS No. [170142-20-8] Order Size Unit Price Stock 5 mg €95.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

ZD 9379

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2261

CAS [170142-20-8]

MF C19H14ClN3O4
MW 383.79

Purity: 100%
Soluble in 0.1N NaOH(aq) and DMSO

ZD 9379

Description

Selective antagonist of the glycine site on the NMDA receptor complex. ZD9379 crosses the blood-brain barrier and is neuroprotective. In vivo studies demonstrated reduced infarct size and less spreading depressions after treatment with ZD 9379.