产品名称 CHPG - (RS)​-​2-​Chloro-​5-​hydroxyphenylglycine | α-Amino-2-chloro-5-hydroxybenzeneacetic acid
产品货号 Axon 2691 CAS [170846-74-9] MF C8H8ClNO3MW 201.61 Purity: 98% Soluble in DMSO Description The mGluR5 receptor agonist CHPG selectively activates mGluR5a receptors (EC50 value of 750 μM), compared to mGluR1α receptors, when expressed in CHO cells. CHPG also potentiates NMDA-induced depolarizations in rat hippocampal slices, and is suggested to act directly on mGluR5 in dopaminergic neurons to induce the release of DA. Also CHPG promotes proliferation of human embryonic cortical NSCs with activation of the MAPKs signaling pathway. KEYWORDS: CHPG | supplier | mGluR5 agonist | CAS [170846-74-9] | Glutamate | mGluR5 | Agonist | Receptors | CAS [1303993-73-8] | CHO | Hippocampus
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CHPG - (RS)​-​2-​Chloro-​5-​hydroxyphenylglycine | α-Amino-2-chloro-5-hydroxybenzeneacetic acid

Based on 111 reference(s) in Google Scholar 8 10 111

Axon 2691

CAS [170846-74-9]

MF C8H8ClNO3
MW 201.61

  • Purity: 98%
  • Soluble in DMSO

CHPG

Description

The mGluR5 receptor agonist CHPG selectively activates mGluR5a receptors (EC50 value of 750 μM), compared to mGluR1α receptors, when expressed in CHO cells. CHPG also potentiates NMDA-induced depolarizations in rat hippocampal slices, and is suggested to act directly on mGluR5 in dopaminergic neurons to induce the release of DA. Also CHPG promotes proliferation of human embryonic cortical NSCs with activation of the MAPKs signaling pathway.

KEYWORDS: CHPG | supplier | mGluR5 agonist | CAS [170846-74-9] | Glutamate | mGluR5 | Agonist | Receptors | CAS [1303993-73-8] | CHO | Hippocampus

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