产品名称 | CHPG - (RS)-2-Chloro-5-hydroxyphenylglycine | α-Amino-2-chloro-5-hydroxybenzeneacetic acid |
产品货号 | Axon 2691 CAS [170846-74-9] MF C8H8ClNO3MW 201.61 Purity: 98% Soluble in DMSO Description The mGluR5 receptor agonist CHPG selectively activates mGluR5a receptors (EC50 value of 750 μM), compared to mGluR1α receptors, when expressed in CHO cells. CHPG also potentiates NMDA-induced depolarizations in rat hippocampal slices, and is suggested to act directly on mGluR5 in dopaminergic neurons to induce the release of DA. Also CHPG promotes proliferation of human embryonic cortical NSCs with activation of the MAPKs signaling pathway. KEYWORDS: CHPG | supplier | mGluR5 agonist | CAS [170846-74-9] | Glutamate | mGluR5 | Agonist | Receptors | CAS [1303993-73-8] | CHO | Hippocampus |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | |
产品品牌 | axonmedchem |
产品概述 | |
产品详情 |
CHPG - (RS)-2-Chloro-5-hydroxyphenylglycine | α-Amino-2-chloro-5-hydroxybenzeneacetic acidAxon 2691 CAS [170846-74-9] MF C8H8ClNO3
DescriptionThe mGluR5 receptor agonist CHPG selectively activates mGluR5a receptors (EC50 value of 750 μM), compared to mGluR1α receptors, when expressed in CHO cells. CHPG also potentiates NMDA-induced depolarizations in rat hippocampal slices, and is suggested to act directly on mGluR5 in dopaminergic neurons to induce the release of DA. Also CHPG promotes proliferation of human embryonic cortical NSCs with activation of the MAPKs signaling pathway. KEYWORDS: CHPG | supplier | mGluR5 agonist | CAS [170846-74-9] | Glutamate | mGluR5 | Agonist | Receptors | CAS [1303993-73-8] | CHO | Hippocampus
mGluR5 agonist
Chemical name2-Amino-2-(2-chloro-5-hydroxyphenyl)acetic acid Parent CAS No.[170846-74-9] |
产品资料 |