产品名称

VU 0357121

产品货号

Axon 1894 CAS [433967-28-3] MF C17H17F2NO2MW 305.32 Purity: 99% Soluble in DMSO Description Potent positive allosteric modulator (PAM) of metabotropic glutamate receptor subtype 5 (mGluR5) (EC50: 33 nM). Binds to a site distinct from that bound by MPEP (Axon 1222) References Certificates Categories Extra info AS Hammond et al. Discovery of a Novel Chemical Class of mGlu(5) Allosteric Ligands with Distinct Modes of Pharmacology. ACS Chem. Neurosci. 2010, 1(10), 702-716. Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation mGluR5 C3 Positive allosteric modulator (PAM) of mGluR5 Chemical name 4-butoxy-N-(2,4-difluorophenyl)benzamide Parent CAS No. [433967-28-3] Order Size Unit Price Stock 10 mg €85.00 In Stock

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axonmedchem

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VU 0357121

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1894

CAS [433967-28-3]

MF C17H17F2NO2
MW 305.32

Purity: 99%
Soluble in DMSO

VU 0357121

Description

Potent positive allosteric modulator (PAM) of metabotropic glutamate receptor subtype 5 (mGluR5) (EC50: 33 nM). Binds to a site distinct from that bound by MPEP (Axon 1222)

AS Hammond et al. Discovery of a Novel Chemical Class of mGlu(5) Allosteric Ligands with Distinct Modes of Pharmacology. ACS Chem. Neurosci. 2010, 1(10), 702-716.

Positive allosteric modulator (PAM) of mGluR5

Chemical name

4-butoxy-N-(2,4-difluorophenyl)benzamide

Parent CAS No.

[433967-28-3]

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