产品名称

CPPHA

产品货号

Axon 1431 CAS [693288-97-0] MF C22H15ClN2O4MW 406.82 Purity: 99% Soluble in DMSO Description A positive allosteric modulator (PAM) of metabotropic glutamate receptor subtype 5 (mGluR5) References Certificates Categories Extra info J O'Brien et al. A novel selective allosteric modulator potentiates the activity of native metabotropic glutamate receptor subtype 5 in rat forebrain. J. Pharmacol. Exp. Ther. 2004, 309, 568-577. Y Chen et al. N-{4-Chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide (CPPHA) Acts through a Novel Site as a Positive Allosteric Modulator of Group 1 Metabotropic Glutamate Receptors. Mol. Pharmacol. 2008, 73, 909-918. Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation mGluR5 C3 Positive allosteric modulator (PAM) of mGluR5 Chemical name N-[4-Chloro-2-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-phenyl]-2-hydroxy-benzamide Parent CAS No. [693288-97-0] Order Size Unit Price Stock 5 mg €95.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

CPPHA

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1431

CAS [693288-97-0]

MF C22H15ClN2O4
MW 406.82

Purity: 99%
Soluble in DMSO

CPPHA

Description

A positive allosteric modulator (PAM) of metabotropic glutamate receptor subtype 5 (mGluR5)

J O'Brien et al. A novel selective allosteric modulator potentiates the activity of native metabotropic glutamate receptor subtype 5 in rat forebrain. J. Pharmacol. Exp. Ther. 2004, 309, 568-577.

Y Chen et al. N-{4-Chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide (CPPHA) Acts through a Novel Site as a Positive Allosteric Modulator of Group 1 Metabotropic Glutamate Receptors. Mol. Pharmacol. 2008, 73, 909-918.

Positive allosteric modulator (PAM) of mGluR5

Chemical name

N-[4-Chloro-2-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-phenyl]-2-hydroxy-benzamide

Parent CAS No.

[693288-97-0]

产品资料