产品名称 JW 55
产品货号 Axon 1922 CAS [664993-53-7] MF C25H26N2O5MW 434.48 Purity: 99% Soluble in DMSO Description A tankyrase (TNKS) inhibitor, inhibiting PARP domain of TNKS1 and TNKS2; JW55 inhibits canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice References Certificates Categories Extra info J Waaler et al. A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice. Cancer Res. 2012, 72(11), 2822-32.  Certificate of Analysis Material Safety Data Sheet Cell Cycle Regulation Cell Signaling & Oncology Stem Cell Wnt-β-Catenin DNA-damage Response EC 2.4.2.30 TNKS Inhibitor of tankyrase (TNKS 1 and 2) Chemical name N-(4-((4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl)methylcarbamoyl)phenyl)furan-2-carboxamide Parent CAS No. [664993-53-7] Order Size Unit Price Stock 10 mg €95.00 In Stock
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JW 55

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1922

CAS [664993-53-7]

MF C25H26N2O5
MW 434.48

  • Purity: 99%
  • Soluble in DMSO

JW 55

Description

A tankyrase (TNKS) inhibitor, inhibiting PARP domain of TNKS1 and TNKS2; JW55 inhibits canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice
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