产品名称

REP 3123 dihydrochloride - CRS3123 dihydrochloride

产品货号

Axon 1705 CAS [1013915-99-5] MF C19H19Br2N3O2S.2HClMW 586.17 Purity: 99% Optical purity: >98% ee Soluble in DMSO Description Selective inhibitor of methionyl-tRNA synthetase (MetRS); agent to treat Clostridium difficile infection (CDI); Antibiotic. KEYWORDS: REP 3123 dihydrochloride | supplier | MetRS inhibitor | CRS3123 dihydrochloride | REP3123 dihydrochloride | REP-3123 dihydrochloride | CRS 3123 dihydrochloride | CRS-3123 dihydrochloride | CAS [1013915-99-5 ] | [1013915-71-3 (absolute | (+)-rotamer)] | DNA-RNA | MetRS | Inhibitor | Enzymes

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

REP 3123 dihydrochloride - CRS3123 dihydrochloride

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1705

CAS [1013915-99-5]

MF C19H19Br2N3O2S.2HCl
MW 586.17

Purity: 99%
Optical purity: >98% ee
Soluble in DMSO

REP 3123 dihydrochloride

Description

Selective inhibitor of methionyl-tRNA synthetase (MetRS); agent to treat Clostridium difficile infection (CDI); Antibiotic.

KEYWORDS: REP 3123 dihydrochloride | supplier | MetRS inhibitor | CRS3123 dihydrochloride | REP3123 dihydrochloride | REP-3123 dihydrochloride | CRS 3123 dihydrochloride | CRS-3123 dihydrochloride | CAS [1013915-99-5 ] | [1013915-71-3 (absolute | (+)-rotamer)] | DNA-RNA | MetRS | Inhibitor | Enzymes

UA Ochsner et al. Inhibitory effect of REP3123 on toxin and spore formation in Clostridium difficile, and in vivo efficacy in a hamster gastrointestinal infection model. J. Antimicrob. Chemother. 2009, 63(5), 964-971.

IA Critchley et al. Spectrum of activity and mode of action of REP3123, a new antibiotic to treat Clostridium difficile infections. J. Antimicrob. Chemother. 2009, 63(5), 954-963.

DM Citron et al. Comparative in vitro activity of REP3123 against Clostridium difficile and other anaerobic intestinal bacteria. J. Antimicrob. Chemother. 2009, 63(5), 972-976.

Cell Signaling & Oncology Immunology MetRS EC 6.1.1.10 Antibiotics

MetRS inhibitor

Chemical name

(R)-5-(3-(6,8-dibromochroman-4-ylamino)propylamino)thieno[3,2-b]pyridin-7(4H)-one dihydrochloride

Parent CAS No.

[1013915-71-3 (absolute, (+)-rotamer)]

产品资料