产品名称

GSK 2636771 dihydrochloride

产品货号

Axon 1912 CAS [1372540-25-4] MF C22H22F3N3O3.2HClMW 506.35 Purity: 99% Soluble in 0.1N NaOH(aq) and DMSO Description Potent, orally available and specific PI3K p110β (PI3K beta, PI3Kβ) inhibitor References Certificates Categories Extra info RA Rivero, MA Hardwick. Identification of GSK2636771, a potent and selective, orally bioavailable inhibitor of phosphatidylinositol 3-kinase-beta (PI3Kβ) for the treatment of PTEN deficient tumors. Cancer Res. 2012, 72(8 Supplement), 2913. RM Sanchez et al. Synthesis and structure–activity relationships of 1,2,4-triazolo[1,5-a]pyrimidin-7(3H)-ones as novel series of potent β isoform selective phosphatidylinositol 3-kinase inhibitors. Bioorg. Med. Chem. Lett. 2012, 22(9), 3198-3202. H Lin. Isoform Selective PI3K-beta Inhibitors. Chin. J. Chem. 2013, 31(3), 299-303. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology PI3K PI3K-Akt-mTOR EC 2.7.1.153 PI3K inhibitor (p110 β specific) Chemical name 2-methyl-1-(2-methyl-3-(trifluoromethyl)benzyl)-6-morpholino-1H-benzo[d]imidazole-4-carboxylic acid dihydrochloride Parent CAS No. [1372540-25-4] Order Size Unit Price Stock 5 mg €105.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

GSK 2636771 dihydrochloride

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1912

CAS [1372540-25-4]

MF C22H22F3N3O3.2HCl
MW 506.35

Purity: 99%
Soluble in 0.1N NaOH(aq) and DMSO

GSK 2636771 dihydrochloride

Description

Potent, orally available and specific PI3K p110β (PI3K beta, PI3Kβ) inhibitor

RA Rivero, MA Hardwick. Identification of GSK2636771, a potent and selective, orally bioavailable inhibitor of phosphatidylinositol 3-kinase-beta (PI3Kβ) for the treatment of PTEN deficient tumors. Cancer Res. 2012, 72(8 Supplement), 2913.

RM Sanchez et al. Synthesis and structure–activity relationships of 1,2,4-triazolo[1,5-a]pyrimidin-7(3H)-ones as novel series of potent β isoform selective phosphatidylinositol 3-kinase inhibitors. Bioorg. Med. Chem. Lett. 2012, 22(9), 3198-3202.

H Lin. Isoform Selective PI3K-beta Inhibitors. Chin. J. Chem. 2013, 31(3), 299-303.

PI3K inhibitor (p110 β specific)

Chemical name

2-methyl-1-(2-methyl-3-(trifluoromethyl)benzyl)-6-morpholino-1H-benzo[d]imidazole-4-carboxylic acid dihydrochloride

Parent CAS No.

[1372540-25-4]

产品资料