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产品名称 Homocamptothecin, (±)-E- - hCPT, dl- | BN 80245
产品货号 Axon 1687 CAS [186668-40-6] MF C21H18N2O4MW 362.38 Purity: 99% Optical purity: racemate Moderately soluble in DMSO Description A potent topoisomerase I (Topo 1) inhibitor; Homocamptothecin (hCPT) is an E-ring modified analogue of camptothecin (CPT), with enhanced stability and potent Topo-1 mediated activity; apoptosis agent References Certificates Categories Extra info L Lesueur-Ginot et al. Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties. Cancer Res. 1999, 59(12), 2939-2943.   O Lavergne et al. Homocamptothecins: Synthesis and Antitumor Activity of Novel E-Ring-Modified Camptothecin Analogues. J. Med. Chem. 1998, 41(27), 5410–5419. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology DNA-damage Response EC 5.99.1.2 TOPO Potent topoisomerase I (Topo 1) inhibitor Chemical name 3H,15H-Oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione, 5-ethyl-1,4,5,13-tetrahydro-5-hydroxy- Parent CAS No. [186668-40-6] Order Size Unit Price Stock 5 mg €135.00 In Stock
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Homocamptothecin, (±)-E- - hCPT, dl- | BN 80245

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1687

CAS [186668-40-6]

MF C21H18N2O4
MW 362.38

  • Purity: 99%
  • Optical purity: racemate
  • Moderately soluble in DMSO

Homocamptothecin, (±)-E-

Description

A potent topoisomerase I (Topo 1) inhibitor; Homocamptothecin (hCPT) is an E-ring modified analogue of camptothecin (CPT), with enhanced stability and potent Topo-1 mediated activity; apoptosis agent
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