| 产品名称 | Bizine |
| 产品货号 | Axon 2306 CAS [N.A.] MF C18H23N3O.HClMW 333.86 Purity: 98% Soluble in water and DMSO Description Potent LSD1 inhibitor in vitro and selective versus monoamine oxidases A/B and the LSD1 homologue, LSD2 with Ki(inact) values 0.059 μM, 2.6 μM, 6.5 μM, and ca 11 μM for LSD1, MAO-A, MAO-B, and LSD2 respectively. Bizine was found to be effective at modulating bulk histone methylation in cancer cells. Moreover, neurons exposed to oxidative stress were protected by the presence of bizine, suggesting potential applications in neurodegenerative disease. References Certificates Categories Extra info P. Prusevich et al. A selective phenelzine analogue inhibitor of histone demethylase LSD1. ACS Chem. Biol. 2014, 9, 1284-1293. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology CNS Epigenetics Immunology EC 1.14.11 Histone demethylase Potent LSD1 inhibitor with selectivity over MAO-A/B, and LSD2 Chemical name N-(4-(2-hydrazinylethyl)phenyl)-4-phenylbutanamide hydrochloride Parent CAS No. [1591932-50-1] Order Size Unit Price Stock 10 mg €120.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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BizineAxon 2306 CAS [N.A.] MF C18H23N3O.HCl
Description
Potent LSD1 inhibitor in vitro and selective versus monoamine oxidases A/B and the LSD1 homologue, LSD2 with Ki(inact) values 0.059 μM, 2.6 μM, 6.5 μM, and ca 11 μM for LSD1, MAO-A, MAO-B, and LSD2 respectively. Bizine was found to be effective at modulating bulk histone methylation in cancer cells. Moreover, neurons exposed to oxidative stress were protected by the presence of bizine, suggesting potential applications in neurodegenerative disease.
Potent LSD1 inhibitor with selectivity over MAO-A/B, and LSD2
Chemical nameN-(4-(2-hydrazinylethyl)phenyl)-4-phenylbutanamide hydrochloride Parent CAS No.[1591932-50-1] |
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