产品名称 YUKA1
产品货号 Axon 2674 CAS [708991-09-7] MF C13H16N4O2SMW 292.36 Purity: 99% Soluble in DMSO Description YUKA1 is a cell-permeable selective inhibitor of lysine demethylase 5A (KDM5A/RBP2/JARID1A) (IC50 value 2.66 μM). YUKA1 blocks drug resistance and cancer cell growth in HeLa cervical cancer cells and ZR-75-1 breast cancer cells. YUKA1 was able to increase H3K4me3 levels in human cells and selectively inhibited the proliferation of cancer cells whose growth depends on KDM5A. KEYWORDS: YUKA1 | supplier | KDM5A inhibitor | YUKA-1 | YUKA 1 | CAS [708991-09-7] | Histone | Histone demethylase | Inhibitor | Enzymes | KDM5A | RBP2 | JARID1A
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YUKA1

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 2674

CAS [708991-09-7]

MF C13H16N4O2S
MW 292.36

  • Purity: 99%
  • Soluble in DMSO

YUKA1

Description

YUKA1 is a cell-permeable selective inhibitor of lysine demethylase 5A (KDM5A/RBP2/JARID1A) (IC50 value 2.66 μM). YUKA1 blocks drug resistance and cancer cell growth in HeLa cervical cancer cells and ZR-75-1 breast cancer cells. YUKA1 was able to increase H3K4me3 levels in human cells and selectively inhibited the proliferation of cancer cells whose growth depends on KDM5A.

KEYWORDS: YUKA1 | supplier | KDM5A inhibitor | YUKA-1 | YUKA 1 | CAS [708991-09-7] | Histone | Histone demethylase | Inhibitor | Enzymes | KDM5A | RBP2 | JARID1A

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