产品名称

ML 324 dihydrochloride

产品货号

Axon 2081 CAS [N.A.] MF C21H23N3O2.2HClMW 422.35 Purity: 100% Soluble in water and DMSO Description Inhibitor of Jumonji domain-containing protein 2 (JMJD2, an "eraser") histone demethylase; effectively blocked herpes simplex virus (HSV) IE gene expression and prevented viral reactivation from latency; >75 fold more efficient than DMOG References Certificates Categories Extra info Y Liang et al. Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency. Sci Transl Med. 2013, 5(167), 167ra5. C Harrison. Comment in Epigenetic drugs: new modulators of readers and erasers. Nat. Rev. Drug Discov. 2013, 12(3), 188. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Epigenetics EC 1.14.11 Histone demethylase Inhibitor of JMJD2 histone demethylase Chemical name N-(3-(dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide dihydrochloride Parent CAS No. [1222800-79-4] Order Size Unit Price Stock 5 mg €125.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

ML 324 dihydrochloride

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2081

CAS [N.A.]

MF C21H23N3O2.2HCl
MW 422.35

Purity: 100%
Soluble in water and DMSO

ML 324 dihydrochloride

Description

Inhibitor of Jumonji domain-containing protein 2 (JMJD2, an "eraser") histone demethylase; effectively blocked herpes simplex virus (HSV) IE gene expression and prevented viral reactivation from latency; >75 fold more efficient than DMOG

Y Liang et al. Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency. Sci Transl Med. 2013, 5(167), 167ra5.

C Harrison. Comment in Epigenetic drugs: new modulators of readers and erasers. Nat. Rev. Drug Discov. 2013, 12(3), 188.

Inhibitor of JMJD2 histone demethylase

Chemical name

N-(3-(dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide dihydrochloride

Parent CAS No.

[1222800-79-4]

产品资料