| 产品名称 | GSK J4 |
| 产品货号 | Axon 1933 CAS [1373423-53-0] MF C24H27N5O2MW 417.50 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Histone demethylase JMJD3/UTX inhibitor; blocks demethylation of histone H3K27; As a cell permeable ethyl ester derivative of GSK J1 (Axon 1934), it is a suitable prodrug form for cell-based studies. It is rapidly hydrolyzed in cells, generateing pharmacologically relevant intracellular concentrations of GSK-J1 References Certificates Categories Extra info L Kruidenier et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature 2012, 488(7411), 404-408. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Epigenetics EC 1.14.11 Histone demethylase Histone demethylase JMJD3/UTX inhibitor Chemical name ethyl 3-(6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-2-yl)pyrimidin-4-ylamino)propanoate Parent CAS No. [1373423-53-0] Order Size Unit Price Stock 5 mg €105.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
GSK J4Axon 1933 CAS [1373423-53-0] MF C24H27N5O2
DescriptionHistone demethylase JMJD3/UTX inhibitor; blocks demethylation of histone H3K27; As a cell permeable ethyl ester derivative of GSK J1 (Axon 1934), it is a suitable prodrug form for cell-based studies. It is rapidly hydrolyzed in cells, generateing pharmacologically relevant intracellular concentrations of GSK-J1
Histone demethylase JMJD3/UTX inhibitor
Chemical nameethyl 3-(6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-2-yl)pyrimidin-4-ylamino)propanoate Parent CAS No.[1373423-53-0] |
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