| 产品名称 | SCH 727965 - Dinaciclib |
| 产品货号 | Axon 1776 CAS [779353-01-4] MF C21H28N6O2MW 396.49 Purity: 99% Optical purity: Optically pure Soluble in 0.1N HCl(aq) and DMSO Description Potent and selective cyclin-dependent kinase (CDK) inhibitor, selectively inhibiting CDK1, CDK2, CDK5 and CDK9 with IC50 values of 3, 1, 1 and 4 nM respectively; a potential antineoplastic agent References Certificates Categories Extra info LS Chen et al. Pim kinase inhibitor, SGI-1776, induces apoptosis in CLL lymphocytes. Blood, 2009, 114 (19), 4150-4157. SM Mumenthaler et al. Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes. Mol. Cancer Ther. 2009, 8(10), 2882-2893. Certificate of Analysis Material Safety Data Sheet Cell Cycle Regulation Cell Signaling & Oncology p53-Tumor Suppression EC 2.7.11.22 CDK CDK inhibitor (1, 2, 5, and 9 specific) Chemical name (S)-3-((3-ethyl-5-(2-(2-hydroxyethyl)piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide Parent CAS No. [779353-01-4] Order Size Unit Price Stock 5 mg €105.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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SCH 727965 - DinaciclibAxon 1776 CAS [779353-01-4] MF C21H28N6O2
Description
Potent and selective cyclin-dependent kinase (CDK) inhibitor, selectively inhibiting CDK1, CDK2, CDK5 and CDK9 with IC50 values of 3, 1, 1 and 4 nM respectively; a potential antineoplastic agent
CDK inhibitor (1, 2, 5, and 9 specific)
Chemical name(S)-3-((3-ethyl-5-(2-(2-hydroxyethyl)piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide Parent CAS No.[779353-01-4] |
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