| 产品名称 | AT 7519 mesylate |
| 产品货号 | Axon 1539 CAS [902135-89-1] MF C16H17Cl2N5O2.CH4O3SMW 478.35 Purity: 99% Soluble in water Description A small molecule inhibitor of multi-CDK, which inhibits CDK 1, 2 , 4, 5, 6, and 9 in vitro and induces apoptosis in multiple myeloma via GSK-3β activation and RNA polymerase II inhibition References Certificates Categories Extra info L Sato et al. AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3β activation and RNA polymerase II inhibition. Oncogene 2010, 29, 2325-2336. MS Squires et al. AT7519, a cyclin-dependent kinase inhibitor, exerts its effects by transcriptional inhibition in leukemia cell lines and patient samples. Mol. Cancer Ther. 2010, 9(4), 920-928. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology p53-Tumor Suppression EC 2.7.11.22 CDK CDK inhibitor Chemical name 4-(2,6-Dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide methanesulfonic acid Parent CAS No. [844442-38-2] Order Size Unit Price Stock 10 mg €80.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
AT 7519 mesylateAxon 1539 CAS [902135-89-1] MF C16H17Cl2N5O2.CH4O3S
Description
A small molecule inhibitor of multi-CDK, which inhibits CDK 1, 2 , 4, 5, 6, and 9 in vitro and induces apoptosis in multiple myeloma via GSK-3β activation and RNA polymerase II inhibition
CDK inhibitor
Chemical name4-(2,6-Dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide methanesulfonic acid Parent CAS No.[844442-38-2] |
| 产品资料 |
