产品名称

PHA-767491

产品货号

Axon 2690 CAS [845714-00-3] MF C12H11N3OMW 213.24 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description PHA-767491 is an ATP mimetic dual CDC7/CDK9 kinase inhibitor (IC50 values of 10 nM and 34 nM for CDC7 and CDK9, respectively). Treatment with PHA-767491 results in apoptotic cell death in multiple cancer cell types and tumor growth inhibition in preclinical cancer models. PHA-767491 is also a potent kinase inhibitor of MAPKAP-K2 (or MK-2) (IC50 value of 171 nM). KEYWORDS: PHA-767491 | supplier | CDC7/CDK9 inhibitor | PHA767491 | PHA 767491 | CAS [845714-00-3] | DNA-RNA | CDC7 | CDK9 | Inhibitor | Enzymes | [942425-68-5] | MK-2 | MAPKAPK2

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

PHA-767491

Based on 16 reference(s) in Google Scholar 8 10 16

Axon 2690

CAS [845714-00-3]

MF C12H11N3O
MW 213.24

Purity: 99%
Soluble in 0.1N HCl(aq) and DMSO

PHA-767491

Description

PHA-767491 is an ATP mimetic dual CDC7/CDK9 kinase inhibitor (IC50 values of 10 nM and 34 nM for CDC7 and CDK9, respectively). Treatment with PHA-767491 results in apoptotic cell death in multiple cancer cell types and tumor growth inhibition in preclinical cancer models. PHA-767491 is also a potent kinase inhibitor of MAPKAP-K2 (or MK-2) (IC50 value of 171 nM).

KEYWORDS: PHA-767491 | supplier | CDC7/CDK9 inhibitor | PHA767491 | PHA 767491 | CAS [845714-00-3] | DNA-RNA | CDC7 | CDK9 | Inhibitor | Enzymes | [942425-68-5] | MK-2 | MAPKAPK2