产品名称 Napabucasin - BBI 608 | FNQ
产品货号 Axon 2517 CAS [83280-65-3] MF C14H8O4MW 240.21 Purity: 99% Soluble in DMSO Description Oral first-in-class cancer stemness (CSCs) inhibitor that works by targeting STAT3. Napabucasin is a naturally occurring drug with enhanced toxicity versus glucose-starved tumor cells, and found to induce Mcl-1 cleavage and sustained phosphorylation of c-Jun-N-terminal kinase. Effectively blocks cancer relapse and metastasis in xenografted human cancers. KEYWORDS: Napabucasin | supplier | STAT3 inhibitor | BBI 608 | FNQ | BBI608 | CAS [83280-65-3] | DNA-RNA | STAT3 | Inhibitor | Transcription Factors | CSCs | cancer stem cell | semness | Mcl-1 | c-Jun-N-terminal kinase | JNK | cancer
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Napabucasin - BBI 608 | FNQ

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2517

CAS [83280-65-3]

MF C14H8O4
MW 240.21

  • Purity: 99%
  • Soluble in DMSO

Napabucasin

Description

Oral first-in-class cancer stemness (CSCs) inhibitor that works by targeting STAT3. Napabucasin is a naturally occurring drug with enhanced toxicity versus glucose-starved tumor cells, and found to induce Mcl-1 cleavage and sustained phosphorylation of c-Jun-N-terminal kinase. Effectively blocks cancer relapse and metastasis in xenografted human cancers.

KEYWORDS: Napabucasin | supplier | STAT3 inhibitor | BBI 608 | FNQ | BBI608 | CAS [83280-65-3] | DNA-RNA | STAT3 | Inhibitor | Transcription Factors | CSCs | cancer stem cell | semness | Mcl-1 | c-Jun-N-terminal kinase | JNK | cancer

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