产品名称 | Napabucasin - BBI 608 | FNQ |
产品货号 | Axon 2517 CAS [83280-65-3] MF C14H8O4MW 240.21 Purity: 99% Soluble in DMSO Description Oral first-in-class cancer stemness (CSCs) inhibitor that works by targeting STAT3. Napabucasin is a naturally occurring drug with enhanced toxicity versus glucose-starved tumor cells, and found to induce Mcl-1 cleavage and sustained phosphorylation of c-Jun-N-terminal kinase. Effectively blocks cancer relapse and metastasis in xenografted human cancers. KEYWORDS: Napabucasin | supplier | STAT3 inhibitor | BBI 608 | FNQ | BBI608 | CAS [83280-65-3] | DNA-RNA | STAT3 | Inhibitor | Transcription Factors | CSCs | cancer stem cell | semness | Mcl-1 | c-Jun-N-terminal kinase | JNK | cancer |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
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Napabucasin - BBI 608 | FNQAxon 2517 CAS [83280-65-3] MF C14H8O4
DescriptionOral first-in-class cancer stemness (CSCs) inhibitor that works by targeting STAT3. Napabucasin is a naturally occurring drug with enhanced toxicity versus glucose-starved tumor cells, and found to induce Mcl-1 cleavage and sustained phosphorylation of c-Jun-N-terminal kinase. Effectively blocks cancer relapse and metastasis in xenografted human cancers. KEYWORDS: Napabucasin | supplier | STAT3 inhibitor | BBI 608 | FNQ | BBI608 | CAS [83280-65-3] | DNA-RNA | STAT3 | Inhibitor | Transcription Factors | CSCs | cancer stem cell | semness | Mcl-1 | c-Jun-N-terminal kinase | JNK | cancer
Oral first-in-class cancer stemness inhibitor that works by targeting STAT3
Chemical name2-acetylbenzo[f][1]benzofuran-4,9-dione Parent CAS No.[83280-65-3] |
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