产品名称

JAK2 inhibitor 13 - Sulfonamide 13

产品货号

Axon 1843 CAS [1110502-30-1] MF C17H20N4O2SMW 344.43 Purity: 99% Soluble in DMSO Description Potent and selective Janus Kinase 2 (JAK2) inhibitor; inhibits the activity of both the wild-type JAK2 and the V617F mutant (IC50 = 78 and 206 nM, respectively), with >35-fold selectivity versus JAK3 (IC50 = 2.93 µM) References Certificates Categories Extra info S Antonysamy et al. Fragment-based discovery of JAK-2 inhibitors. Bioorg. Med. Chem. Lett. 2009, 19(1), 279-282. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Epigenetics JAK-STAT EC 2.7.10.2 JAK JAK2 inhibitor Chemical name 4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide Parent CAS No. [1110502-30-1] Order Size Unit Price Stock 5 mg €105.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

JAK2 inhibitor 13 - Sulfonamide 13

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1843

CAS [1110502-30-1]

MF C17H20N4O2S
MW 344.43

Purity: 99%
Soluble in DMSO

JAK2 inhibitor 13

Description

Potent and selective Janus Kinase 2 (JAK2) inhibitor; inhibits the activity of both the wild-type JAK2 and the V617F mutant (IC50 = 78 and 206 nM, respectively), with >35-fold selectivity versus JAK3 (IC50 = 2.93 µM)

S Antonysamy et al. Fragment-based discovery of JAK-2 inhibitors. Bioorg. Med. Chem. Lett. 2009, 19(1), 279-282.

JAK2 inhibitor

Chemical name

4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide

Parent CAS No.

[1110502-30-1]

产品资料