| 产品名称 | AZ 960 |
| 产品货号 | Axon 1778 CAS [905586-69-8] MF C18H16F2N6MW 354.36 Purity: 98% Optical purity: Optically pure Soluble in DMSO Description Potent, selective and ATP-competitive JAK2 inhibitor; AZ960 inhibits JAK2 kinase with a Ki of 0.45 nM in vitro and induces growth arrest and apoptosis in adult T-cell leukemia (ATL) cell References Certificates Categories Extra info JM Gozgit et al. Effects of the JAK2 Inhibitor, AZ960, on Pim/BAD/BCL-xL Survival Signaling in the Human JAK2 V617F Cell Line SET-2. J. Biol. Chem. 2008, 283(47), 32334-32343. J Yang et al. AZ960, a novel Jak2 inhibitor, induces growth arrest and apoptosis in adult T-cell leukemia cells. Mol Cancer Ther. 2010, 9(12), 3386-3395. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology Epigenetics JAK-STAT EC 2.7.10.2 JAK JAK2 inhibitor Chemical name (S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5-methyl-1H-pyrazol-3-ylamino)nicotinonitrile Parent CAS No. [905586-69-8] Order Size Unit Price Stock 2 mg €95.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
AZ 960Axon 1778 CAS [905586-69-8] MF C18H16F2N6
Description
Potent, selective and ATP-competitive JAK2 inhibitor; AZ960 inhibits JAK2 kinase with a Ki of 0.45 nM in vitro and induces growth arrest and apoptosis in adult T-cell leukemia (ATL) cell
JAK2 inhibitor
Chemical name(S)-5-fluoro-2-(1-(4-fluorophenyl)ethylamino)-6-(5-methyl-1H-pyrazol-3-ylamino)nicotinonitrile Parent CAS No.[905586-69-8] |
| 产品资料 |
