| 产品名称 | UPF 648 |
| 产品货号 | Axon 2118 CAS [213400-34-1] MF C11H8Cl2O3MW 259.09 Purity: 99% Optical purity: Optically pure Soluble in 0.1N NaOH(aq) and DMSO Description Potent and selective inhibitor of kynurenine-3-monooxygenase (KMO, or kynurenine hydroxylase) activity (IC50: 20 nM); Active (+)-(1S,2S)-enantiomer; Useful tool for research on cognitive enhancement and neuroprotection in the brain. References Certificates Categories Extra info R. Pellicciari et al. Modulation of the kynurenine pathway of tryptophan metabolism in search for neuroprotective agents. Focus on kynurenine-3-hydroxylase. Adv. Exp. Med. Biol. 2003, 527, 621–628. MT Sapko et al. Endogenous kynurenate controls the vulnerability of striatal neurons to quinolinate: implications for Huntington's disease. Exp. Neurol. 2006, 197(1), 31-40. L Amori et al. On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo. J. Neurochem. 2009, 109(2), 316-325. M Amaral et al. Structural basis of kynurenine 3-monooxygenase inhibition. Nature 2013, 496, 382–385. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology CNS Pain & Inflammation KMO EC 1.14.13.9 Potent inhibitor of kynurenine-3-monooxygenase (KMO) Chemical name (1S,2S)-2-(3,4-dichlorobenzoyl)cyclopropanecarboxylic acid Parent CAS No. [213400-34-1] Order Size Unit Price Stock 2 mg €115.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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| 产品详情 |
UPF 648Axon 2118 CAS [213400-34-1] MF C11H8Cl2O3
Description
Potent and selective inhibitor of kynurenine-3-monooxygenase (KMO, or kynurenine hydroxylase) activity (IC50: 20 nM); Active (+)-(1S,2S)-enantiomer; Useful tool for research on cognitive enhancement and neuroprotection in the brain.
Potent inhibitor of kynurenine-3-monooxygenase (KMO)
Chemical name(1S,2S)-2-(3,4-dichlorobenzoyl)cyclopropanecarboxylic acid Parent CAS No.[213400-34-1] |
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