| 产品名称 | RO 61-8048 |
| 产品货号 | Axon 2139 CAS [199666-03-0] MF C17H15N3O6S2MW 421.45 Purity: 99% Soluble in DMSO Description Potent, selective and reversible inhibitor of kynurenine-3-monooxygenase (KMO, or kynurenine hydroxylase) activity (IC50: 37 nM); cell-permeable and competitive References Certificates Categories Extra info R. Cozzi et al. Kynurenine hydroxylase inhibitors reduce ischaemic brain damage: studies with (m-nitrobenzoyl)alanine and 3,4-dimethoxy-[N-4-(nitrophenyl)thiazol-2-yl]-benzenesulfonamide (...). J. Cereb. Blood Flow Metab., 1999, 19, 771–777. A. Chiarugi, F. Moroni. Quinolinic acid formation in immuno-activated mice: studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[N-4-(3-nitrophenyl)thiazol-2-yl[benzenesulphonamide (Ro61-8048), (...). Neuropharmacol. 1999, 38, 1225–1233. TW Stone. Development and therapeutic potential of kynurenic acid and kynurenine derivatives for neuroprotection. Trends in Pharmacol. Sci. 2000, 21(4), 149–154. Certificate of Analysis Material Safety Data Sheet Cardiovascular CNS Pain & Inflammation KMO EC 1.14.13.9 Inhibitor of kynurenine-3-monooxygenase (KMO) Chemical name 3,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonamide Parent CAS No. [199666-03-0] Order Size Unit Price Stock 10 mg €95.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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RO 61-8048Axon 2139 CAS [199666-03-0] MF C17H15N3O6S2
Description
Potent, selective and reversible inhibitor of kynurenine-3-monooxygenase (KMO, or kynurenine hydroxylase) activity (IC50: 37 nM); cell-permeable and competitive
Inhibitor of kynurenine-3-monooxygenase (KMO)
Chemical name3,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonamide Parent CAS No.[199666-03-0] |
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