产品名称

AG 490 - Tyrphostin AG 490 | Tyrphostin B42

产品货号

Axon 1378 CAS [133550-30-8] MF C17H14N2O3MW 294.30 Purity: 99% Soluble in 0.1N NaOH(aq), DMSO, and Ethanol Description Janus Kinase 2 (JAK2) inhibitor References Certificates Categories Extra info N Miyamoto et al. The JAK2 inhibitor AG490 predominantly abrogates the growth of human B-precursor leukemic cells with 11q23 translocation or Philadelphia chromosome. Leukemia 2001, 15, 1758-1768. O Sareila et al. JAK Inhibitors AG-490 and WHI-P154 Decrease IFN-γ-Induced iNOS Expression and NO Production in Macrophages. Mediators Inflamm. 2006,2006(2), 16161. N Meydan, et al. Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor.Nature 1996, 379, 645-648. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Epigenetics JAK-STAT EC 2.7.10.2 JAK JAK2 inhibitor Chemical name (E)-N-Benzyl-2-cyano-3-(3,4-dihydro xy-phenyl)-acrylamide Parent CAS No. [133550-30-8] Order Size Unit Price Stock 10 mg €65.00 In Stock

产品价格

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产品规格

产品品牌

axonmedchem

产品概述

产品详情

AG 490 - Tyrphostin AG 490 | Tyrphostin B42

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1378

CAS [133550-30-8]

MF C17H14N2O3
MW 294.30

Purity: 99%
Soluble in 0.1N NaOH(aq), DMSO, and Ethanol

AG 490

Description

Janus Kinase 2 (JAK2) inhibitor

N Miyamoto et al. The JAK2 inhibitor AG490 predominantly abrogates the growth of human B-precursor leukemic cells with 11q23 translocation or Philadelphia chromosome. Leukemia 2001, 15, 1758-1768.

O Sareila et al. JAK Inhibitors AG-490 and WHI-P154 Decrease IFN-γ-Induced iNOS Expression and NO Production in Macrophages. Mediators Inflamm. 2006,2006(2), 16161.

N Meydan, et al. Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor.Nature 1996, 379, 645-648.

JAK2 inhibitor

Chemical name

(E)-N-Benzyl-2-cyano-3-(3,4-dihydro xy-phenyl)-acrylamide

Parent CAS No.

[133550-30-8]

产品资料