产品名称 | Sildenafil citrate - Viagra | UK 92480 |
产品货号 | Axon 2046 CAS [171599-83-0] MF C22H30N6O4S.C6H8O7MW 666.70 Purity: 100% Soluble in DMSO Description Potent and selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) with IC50 value of 4 nM; Enhances nitric oxide (NO)-dependent relaxation of human corpus cavernosum in vitro; an oral therapy for erectile dysfunction (ED) References Certificates Categories Extra info M Boolell et al. Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction. Int. J. Impot. Res. 1996, 8 (2), 47–52. I Goldstein et al. Oral Sildenafil in the Treatment of Erectile Dysfunction. N. Engl. J. Med. 1998, 338, 1397-1404. Certificate of Analysis Material Safety Data Sheet Cardiovascular Cell Signaling & Oncology CNS EC 3.1.4.35 PDE Pfizer Licensed Products Inhibitor of cGMP-specific PDE5 Chemical name 5-(2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one 2-hydroxypropane-1,2,3-tricarboxylate Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [139755-83-2] Order Size Unit Price Stock 10 mg €80.00 In Stock |
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产品品牌 | axonmedchem |
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Sildenafil citrate - Viagra | UK 92480Axon 2046 CAS [171599-83-0] MF C22H30N6O4S.C6H8O7
Description
Potent and selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) with IC50 value of 4 nM; Enhances nitric oxide (NO)-dependent relaxation of human corpus cavernosum in vitro; an oral therapy for erectile dysfunction (ED)
Inhibitor of cGMP-specific PDE5
Chemical name5-(2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one 2-hydroxypropane-1,2,3-tricarboxylate Source informationPfizer compound; Sold for research purposes under agreement from Pfizer Inc.Parent CAS No.[139755-83-2] |
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