产品名称

Rolipram, (S)-(+)-

产品货号

Axon 1432 CAS [85416-73-5] MF C16H21NO3MW 275.34 Purity: 99% Soluble in DMSO and Ethanol Description PDE4 inhibitor, less active S-enantiomer of Rolipram (Axon 1212) in comparison with the opposite (R)-(-)-Rolipram (Axon 1229) References Certificates Categories Extra info HH Schneider et al. Stereospecific binding of the antidepressant rolipram to brain protein structures. Eur. J. Pharmacol. 1986, 127(1-2), 105-15. DE Griswold et al. Effect of selective phosphodiesterase type IV inhibitor, rolipram, on fluid and cellular phases of inflammatory response. Inflammation. 1993, 17(3), 333–44. SJ Kanes et al. Rolipram: A specific phosphodiesterase 4 inhibitor with potential antipsychotic activity. Neuroscience. 2006, 144, 239-46. RW Chen et al. Broad spectrum neuroprotection profile of phosphodiesterase inhibitors as related to modulation of cell-cycle elements and caspase-3 activation. Neuroscience Letters. 2007, 418(2), 165–9. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology CNS Pain & Inflammation EC 3.1.4.53 PDE PDE4 inhibitor Chemical name (4S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one Parent CAS No. [85416-73-5] Order Size Unit Price Stock 10 mg €115.00 In Stock

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产品概述

产品详情

Rolipram, (S)-(+)-

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1432

CAS [85416-73-5]

MF C16H21NO3
MW 275.34

Purity: 99%
Soluble in DMSO and Ethanol

Rolipram, (S)-(+)-

Description

PDE4 inhibitor, less active S-enantiomer of Rolipram (Axon 1212) in comparison with the opposite (R)-(-)-Rolipram (Axon 1229)

HH Schneider et al. Stereospecific binding of the antidepressant rolipram to brain protein structures. Eur. J. Pharmacol. 1986, 127(1-2), 105-15.

DE Griswold et al. Effect of selective phosphodiesterase type IV inhibitor, rolipram, on fluid and cellular phases of inflammatory response. Inflammation. 1993, 17(3), 333–44.

SJ Kanes et al. Rolipram: A specific phosphodiesterase 4 inhibitor with potential antipsychotic activity. Neuroscience. 2006, 144, 239-46.

RW Chen et al. Broad spectrum neuroprotection profile of phosphodiesterase inhibitors as related to modulation of cell-cycle elements and caspase-3 activation. Neuroscience Letters. 2007, 418(2), 165–9.

PDE4 inhibitor

Chemical name

(4S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one

Parent CAS No.

[85416-73-5]

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