联系方式：400-650-8506
CNEN
产品名称 SCH 442416, Desmethyl
产品货号 Axon 2283 CAS [188112-92-7] MF C19H17N7O2MW 375.38 Purity: 95% Soluble in DMSO Description Precursor for [11C]SCH442416 for PET studies; Radioligand precursor of the highly selective and potent A2A adenosine receptor antagonist SCH 442416 (Axon 1264). Desmethyl SCH 442416 is less potent and less selective in binding the A2A receptor than SCH 445416 (Ki values 44 nM, 48 nM, and 34 nM for A1, A2A and A3 respectively). References Certificates Categories Extra info K. Ishiwata et al. PET Tracers for mapping adenosine receptors as probes for diagnosis of CNS disorders. CNS Agents Med. Chem. 2007, 7, 55-57.   Toddle et al. Design, radiosynthesis, and biodistribution of a new potent and selective ligand for in vivo imaging of the adenosine A2A receptor system using positron emission tomography. J. Med. Chem. 2000, 43, 4359.   A.K. Bhattacharjee et al. Striatal adenosine A2A receptor mediated PET Imaging in 6-hydroxydopamine lesioned rats using [18F]-MRS5425. Nucl. Med. Biol. 2011, 38, 897-906.   B.A. Shinkre et al. Synthesis and evaluation of 1,2,4-triazolo[1,5-c]pyrimidine derivatives as A2A receptor-selective antagonists. Bioorg. Med. Chem. Lett. 2010, 20, 5690-5694. Certificate of Analysis Material Safety Data Sheet Cardiovascular CNS A1 A2A A3 A18 Non Selective Radioligand precursor of the adenosine A2A antagonist SCH 442416 Chemical name 4-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)phenol Parent CAS No. [188112-92-7] Order Size Unit Price Stock 10 mg €300.00 In Stock
产品价格 现货询价，电话：010-67529703
产品规格
产品品牌 axonmedchem
产品概述
产品详情

SCH 442416, Desmethyl

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2283

CAS [188112-92-7]

MF C19H17N7O2
MW 375.38

  • Purity: 95%
  • Soluble in DMSO

SCH 442416, Desmethyl

Description

Precursor for [11C]SCH442416 for PET studies; Radioligand precursor of the highly selective and potent A2A adenosine receptor antagonist SCH 442416 (Axon 1264). Desmethyl SCH 442416 is less potent and less selective in binding the A2A receptor than SCH 445416 (Ki values 44 nM, 48 nM, and 34 nM for A1, A2A and A3 respectively).
产品资料