产品名称

KW 6002 - Istradefylline

产品货号

Axon 1423 CAS [155270-99-8] MF C20H24N4O4MW 384.43 Purity: 99% Soluble in DMSO Description Very potent, selective and orally active adenosine A2A receptor antagonist in experimental models of Parkinson's disease References Certificates Categories Extra info S Shiozaki et al. Actions of adenosine A2A receptor antagonist KW-6002 on drug-induced catalepsy and hypokinesia caused by reserpine or MPTP. Psychopharmacology (Berl). 1999, 147(1), 90-95. TN Chase et al. Translating A2A antagonist KW6002 from animal models to parkinsonian patients. Neurology 2003, 61(11 Suppl 6), S107-11. PA LeWitt et al. Adenosine A2A receptor antagonist istradefylline (KW-6002) reduces "off" time in Parkinson's disease: a double-blind, randomized, multicenter clinical trial (6002-US-005). Ann. Neurol. 2008, 63(3), 295-302. Certificate of Analysis Material Safety Data Sheet Cardiovascular CNS A2A A18 Adenosine A2A antagonist Chemical name 8-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-1,3-diethyl-7-methyl-3,7-dihydro-purine-2,6-dione Parent CAS No. [155270-99-8] Order Size Unit Price Stock 5 mg €85.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

KW 6002 - Istradefylline

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1423

CAS [155270-99-8]

MF C20H24N4O4
MW 384.43

Purity: 99%
Soluble in DMSO

KW 6002

Description

Very potent, selective and orally active adenosine A2A receptor antagonist in experimental models of Parkinson's disease

S Shiozaki et al. Actions of adenosine A2A receptor antagonist KW-6002 on drug-induced catalepsy and hypokinesia caused by reserpine or MPTP. Psychopharmacology (Berl). 1999, 147(1), 90-95.

TN Chase et al. Translating A2A antagonist KW6002 from animal models to parkinsonian patients. Neurology 2003, 61(11 Suppl 6), S107-11.

PA LeWitt et al. Adenosine A2A receptor antagonist istradefylline (KW-6002) reduces "off" time in Parkinson's disease: a double-blind, randomized, multicenter clinical trial (6002-US-005). Ann. Neurol. 2008, 63(3), 295-302.

Adenosine A2A antagonist

Chemical name

8-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-1,3-diethyl-7-methyl-3,7-dihydro-purine-2,6-dione

Parent CAS No.

[155270-99-8]

产品资料