产品名称

Deazaadenosine, 1-

产品货号

Axon 2434 CAS [14432-09-8] MF C11H14N4O4MW 266.25 Purity: 99% Optical purity: Optically pure Soluble in 0.1N HCl(aq) and DMSO Description Inhibitor of adenosine deaminase (ADA; IC50 value 0.38 μM) 1-Deazaadenosine showed cytostatic activity against multiple cell lines in vitro. KEYWORDS: 1-Deazaadenosine | supplier | ADA inhibitor | CAS [14432-09-8] | Adenosine | deaminase | cytostatic | antitumor

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

Deazaadenosine, 1-

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2434

CAS [14432-09-8]

MF C11H14N4O4
MW 266.25

Purity: 99%
Optical purity: Optically pure
Soluble in 0.1N HCl(aq) and DMSO

Deazaadenosine, 1-

Description

Inhibitor of adenosine deaminase (ADA; IC50 value 0.38 μM) 1-Deazaadenosine showed cytostatic activity against multiple cell lines in vitro.

S. Costanzi et al. 3'-deoxyribofuranose derivatives of 1-deaza and 3-deaza-adenosine and their activity as adenosine deaminase inhibitors. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):1037-41.

G. Cristalli et al. Improved synthesis and antitumor activity of 1-deazaadenosine. J Med Chem. 1987 Sep;30(9):1686-8.

F. Seela et al. 1-Deazaadenosine: synthesis and activity of base-modified hammerhead ribozymes. Nucleic Acids Res. 1998 Feb 15;26(4):1010-8.

Adenosine deaminase (ADA) inhibitor with cytostatic activity in vitro

Chemical name

(2R,3R,4S,5R)-2-(7-amino-3H-imidazo[4,5-b]pyridin-3-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Parent CAS No.

[14432-09-8]

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