SCH 442416

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1264

CAS [316173-57-6]

MF C20H19N7O2
MW 389.41

Purity: 99%
Soluble in DMSO

SCH 442416

Description

Highly selective and potent A2A adenosine receptor antagonist.

The desmethyl derivative of SCH 442416 (Axon 2283) is a valuable precursor for [11C]SCH442416 PET studies, and is available from Axon Medchem as well.

Toddle et al. Design, radiosynthesis, and biodistribution of a new potent and selective ligand for in vivo imaging of the adenosine A2A receptor system using positron emission tomography. J. Med. Chem. 2000, 43, 4359.

B.A. Shinkre et al. Synthesis and evaluation of 1,2,4-triazolo[1,5-c]pyrimidine derivatives as A2A receptor-selective antagonists. Bioorg. Med. Chem. Lett. 2010, 20, 5690-5694.

Adenosine A2A antagonist

Chemical name

2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine

Parent CAS No.

[316173-57-6]

产品资料