| 产品名称 | Gö 6983 - GO 6983 | Goe 6983 | |
| 产品货号 | Axon 2466 CAS [133053-19-7] MF C26H26N4O3MW 442.51 Purity: 99% Soluble in DMSO Description Broad spectrum PKC inhibitor lacking inhibitory effect for the PKCμ isotype (IC50 values ranging from 7-60 nM for PKCα-PKCζ , and 20000 nM for PKCμ, respectively). Gö6983 significantly enhanced ERK1/2 activity not only in IL-6-stimulated cells, but also the basal ERK1/2 activity in non-stimulated cells; yet, it has no effect on IL-6-triggered B9 cell proliferation, suggesting a crucial role for PKCμ. Useful tool for isolation, generation, derivatization and stabilization of naive human pluripotent stem cells in so called NHSM conditions developed at the Weizmann Institute of Science. *Promotion | |
| 产品价格 | 现货询价，电话：010-67529703 | |
| 产品规格 | ||
| 产品品牌 | axonmedchem | |
| 产品概述 | ||
| 产品详情 |
Gö 6983 - GO 6983 | Goe 6983Axon 2466 CAS [133053-19-7] MF C26H26N4O3
DescriptionBroad spectrum PKC inhibitor lacking inhibitory effect for the PKCμ isotype (IC50 values ranging from 7-60 nM for PKCα-PKCζ , and 20000 nM for PKCμ, respectively). Gö6983 significantly enhanced ERK1/2 activity not only in IL-6-stimulated cells, but also the basal ERK1/2 activity in non-stimulated cells; yet, it has no effect on IL-6-triggered B9 cell proliferation, suggesting a crucial role for PKCμ. Useful tool for isolation, generation, derivatization and stabilization of naive human pluripotent stem cells in so called NHSM conditions developed at the Weizmann Institute of Science. *Promotion: Gö 6983 is also part of Inhibitor Set(s):
Broad spectrum PKC inhibitor lacking inhibitory effect for PKCμ
Chemical name3-(1-(3-(dimethylamino)propyl)-5-methoxy-1H-indol-3-yl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione Parent CAS No.[133053-19-7] |
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