产品名称 CP 724714
产品货号 Axon 1537 CAS [383432-38-0] MF C27H27N5O3MW 469.53 Purity: 98% Soluble in DMSO Description A oral, selective and potent ErbB-2 (HER2) kinase inhibitor; reported to inhibit HER2-driven cell line References Certificates Categories Extra info JP Jani et al. Discovery and Pharmacologic Characterization of CP-724,714, a Selective ErbB2 Tyrosine Kinase Inhibitor. Cancer Res. 2007, 67(20), 9887-9893.    PN Munster et al. First Study of the Safety, Tolerability, and Pharmacokinetics of CP-724,714 in Patients with Advanced Malignant Solid HER2-Expressing Tumors. Clin. Cancer Res. 2007, 13, 1238-1245.    F Guo et al. Pharmacokinetics of a HER2 tyrosine kinase inhibitor CP-724,714 in patients with advanced malignant HER2 positive solid tumors: correlations with clinical characteristics and safety. Cancer Chemother. Pharmacol. 2008, 62(1), 97-109.  Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology ErbB2-HER2 JAK-STAT RTK class I; EC 2.7.10.1 ErbB-2/HER2 kinase inhibitor Chemical name 2-Methoxy-N-((E)-3-{4-[3-methyl-4-(6-methyl-pyridin-3-yloxy)-phenylamino]-quinazolin-6-yl}-allyl)-acetamide Parent CAS No. [383432-38-0] Order Size Unit Price Stock 2 mg €80.00 In Stock
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