| 产品名称 | FC 99 hydrochloride |
| 产品货号 | Axon 2318 CAS [N.A.] MF C15H18N2O.xHClMW 304.30 Purity: 98% Soluble in water and DMSO Description Inhibitor of TLR3 expression and inflammatory responses induced by a synthetic dsRNA (poly(I:C)) and by exogenous IFN-α via IRF3. FC-99 suppressed the phosphorylation levels of ERK, JNK, and p38 in varying degrees without altering the total protein The ability of FC-99 to reverse TLR3 expression may account for its marked effect on the model of sepsis. References Certificates Categories Extra info W. Gong et al. A novel 1,2-benzenediamine derivative FC-99 suppresses TLR3 expression and ameliorates disease symptoms in a mouse model of sepsis. Br. J. Pharmacol. 2014, 171, 4866-4878. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Immunology Pain & Inflammation NF-κB JAK-STAT TLR3 TLR3 Inhibitor of TLR3 expression and inflammatory responses. Chemical name N1-(4-methoxybenzyl)-4-methylbenzene-1,2-diamine hydrochloride (1:1.7) Parent CAS No. [1097810-71-3] Order Size Unit Price Stock 5 mg €95.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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FC 99 hydrochlorideAxon 2318 CAS [N.A.] MF C15H18N2O.xHCl
Description
Inhibitor of TLR3 expression and inflammatory responses induced by a synthetic dsRNA (poly(I:C)) and by exogenous IFN-α via IRF3. FC-99 suppressed the phosphorylation levels of ERK, JNK, and p38 in varying degrees without altering the total protein The ability of FC-99 to reverse TLR3 expression may account for its marked effect on the model of sepsis.
Inhibitor of TLR3 expression and inflammatory responses.
Chemical nameN1-(4-methoxybenzyl)-4-methylbenzene-1,2-diamine hydrochloride (1:1.7) Parent CAS No.[1097810-71-3] |
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