产品名称 | CU-T12-9 |
产品货号 | Axon 2455 CAS [1821387-73-8] MF C17H13F3N4O2MW 362.31 Purity: 100% Soluble in DMSO Description Selective TLR1/TLR2 agonist (IC50 value 54.4 nM in a competitive binding assay with Pam3CSK4) that facilitates the TLR1/2 heterodimeric complex formation, but not TLR2/6 complex formation. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and inducible NOS. KEYWORDS: CU-T12-9 | Supplier | TLR1/2 agonist | CUT129 | CAS [1821387-73-8] | DNA-RNA | TLR1 | TLR2 | Modulator | Toll-like receptor | immunology | virus | NF-κB | TNF-α | IL-10 | NOS | vaccine adjuvant | antitumor | interleukin | T-cell |
产品价格 | 现货询价,电话:010-67529703 |
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产品品牌 | axonmedchem |
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CU-T12-9Axon 2455 CAS [1821387-73-8] MF C17H13F3N4O2
DescriptionSelective TLR1/TLR2 agonist (IC50 value 54.4 nM in a competitive binding assay with Pam3CSK4) that facilitates the TLR1/2 heterodimeric complex formation, but not TLR2/6 complex formation. CU-T12-9 signals through NF-κB and invokes an elevation of the downstream effectors TNF-α, IL-10, and inducible NOS. KEYWORDS: CU-T12-9 | Supplier | TLR1/2 agonist | CUT129 | CAS [1821387-73-8] | DNA-RNA | TLR1 | TLR2 | Modulator | Toll-like receptor | immunology | virus | NF-κB | TNF-α | IL-10 | NOS | vaccine adjuvant | antitumor | interleukin | T-cell
Selective TLR1/TLR2 agonist that facilitates the TLR1/2 complex formation
Chemical nameN-methyl-4-nitro-2-(4-(4-(trifluoromethyl)phenyl)-1H-imidazol-1-yl)aniline Parent CAS No.[1821387-73-8] |
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