| 产品名称 | AZD 1981 |
| 产品货号 | Axon 2145 CAS [802904-66-1] MF C19H17ClN2O3SMW 388.87 Purity: 99% Soluble in 0.1N NaOH(aq) and DMSO Description Potent, orally bio-available and selective CRTh2 (also known as DP2) antagonist; AZD1981 inhibited PGD2 binding to human CRTh2 with an IC50 of 4 nM References Certificates Categories Extra info JA Schmidt et al. Biochemical and pharmacological characterization of AZD1981, an orally available selective DP2 antagonist in clinical development for asthma. Br. J. Pharmacol. 2013, 168(7), 1626-1638. N Snell et al. Efficacy and safety of AZD1981, a CRTH2 receptor antagonist, in patients with moderate to severe COPD. Respir Med. 2013 Jul 1. pii: S0954-6111(13)00218-7. T Luker et al. Substituted indole-1-acetic acids as potent and selective CRTh2 antagonists-discovery of AZD1981. Bioorg. Med. Chem. Lett. 2011, 21(21), 6288-6292. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Pain & Inflammation CRTH2 A14 Selective CRTH2 (aka DP2) antagonist Chemical name 2-(4-acetamido-3-(4-chlorophenylthio)-2-methyl-1H-indol-1-yl)acetic acid Parent CAS No. [802904-66-1] Order Size Unit Price Stock 5 mg €105.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
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AZD 1981Axon 2145 CAS [802904-66-1] MF C19H17ClN2O3S
Description
Potent, orally bio-available and selective CRTh2 (also known as DP2) antagonist; AZD1981 inhibited PGD2 binding to human CRTh2 with an IC50 of 4 nM
Selective CRTH2 (aka DP2) antagonist
Chemical name2-(4-acetamido-3-(4-chlorophenylthio)-2-methyl-1H-indol-1-yl)acetic acid Parent CAS No.[802904-66-1] |
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